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| High mobility group ： ウィキペディア英語版 |
High-mobility group
High-Mobility Group or HMG is a group of chromosomal proteins that are involved in the regulation of DNA-dependent processes such as
transcription, replication, recombination, and DNA repair.
==Families==
The HMG proteins are subdivided into 3 superfamilies each containing a characteristic functional domain:
* HMGA – contains an AT-hook domain
*
* HMGA1
*
* HMGA2
* HMGB – contains a HMG-box domain
*
* HMGB1
*
* HMGB2
*
* HMGB3
*
* HMGB4
* HMGN – contains a nucleosomal binding domain
*
* HMGN1
*
* HMGN2
*
* HMGN3
*
* HMGN4
* Sex-Determining Region Y Protein
* TCF Transcription Factors
*
* Lymphoid enhancer-binding factor 1
*
* T Cell Transcription Factor 1
Proteins containing any of these embedded in their sequence are known as HMG motif proteins.
HMG-box proteins are found in a variety of eukaryotic organisms.
They were originally isolated from mammalian cells, and named according to their electrophoretic mobility in polyacrylamide gels.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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